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Writer's pictureDr. Emma Clark

Liver Disease in Cats


A cat sleeping on a blanket

Liver disease in cats is a significant health issue that requires prompt attention. It encompasses various conditions that affect the liver's ability to function properly. 


Early detection and treatment are crucial in managing the disease and improving outcomes for affected cats. 


This article aims to provide comprehensive information on liver disease in cats, including its types, functions of the liver, signs and symptoms, causes, diagnosis, treatment options, prognosis, and prevention.


The Role of the Liver

The liver is a vital organ with numerous functions essential for maintaining overall health in cats. The liver's primary functions include detoxification, metabolism and storage, and immune system regulation.


The liver detoxifies harmful substances from the blood, converting them into harmless compounds that are then excreted from the body. This process is crucial for preventing the buildup of toxins that can lead to severe health issues.


The liver also plays a central role in metabolism by processing nutrients from food and storing energy in the form of glycogen. It also metabolises fats and proteins, ensuring that the body has a steady supply of energy.


Finally, the liver helps regulate the immune system by producing proteins involved in immune responses and filtering out bacteria and other pathogens from the blood. This function is vital for protecting the body against infections and diseases.


What is Liver Disease in Cats?

Liver disease refers to any condition that impairs the liver's function. It can be classified into acute and chronic forms, with each presenting different challenges in diagnosis and treatment.


Acute vs Chronic Liver Disease

Acute liver disease occurs suddenly and can be life-threatening. It often results from toxins, infections, or trauma. Chronic liver disease develops over time, usually due to long-term damage or underlying health issues such as genetic predispositions or metabolic disorders. Both forms require different approaches to treatment and management.


Hepatic Lipidosis (Fatty Liver Disease)

Hepatic lipidosis, commonly known as fatty liver disease, is a prevalent type of liver disease in cats. It occurs when an excessive amount of fat accumulates in the liver cells, impairing liver function. This condition is particularly common in overweight cats and those that experience rapid weight loss.


Signs and Symptoms of Liver Disease

A cat's eyes

Recognising the signs of liver disease early can significantly impact the treatment and prognosis for affected cats.


Early symptoms of liver disease in cats can be subtle and easily overlooked. They may include lethargy, decreased appetite, and weight loss. These signs indicate that the liver is struggling to perform its functions effectively.


As the disease progresses, more severe symptoms can develop, signalling significant liver dysfunction.


Jaundice

Jaundice is a common sign of advanced liver disease. It causes a yellowing of the skin, eyes, and mucous membranes due to the buildup of bilirubin, a byproduct of red blood cell breakdown.


Neurological Symptoms

Neurological symptoms, such as disorientation, seizures, and changes in behaviour, can occur when toxins that the liver usually filters out accumulate in the bloodstream and affect the brain.


Causes of Liver Disease

Bacterial, viral, and fungal infections can lead to liver disease by directly damaging liver cells or causing inflammation.


Exposure to toxins, including certain medications, chemicals, and plants, can cause acute liver damage. Common household substances like antifreeze and certain human medications are particularly dangerous to cats.


Some cats are genetically predisposed to liver disease, making them more susceptible to developing the condition. Breeds like the Siamese are known to have a higher risk of certain liver diseases.


Other causes of liver disease include trauma, cancer, and inflammatory conditions such as cholangitis, which is inflammation of the bile ducts.


Diagnosis of Liver Disease

A cat being diagnosed with liver disease by a vet

Diagnosing liver disease involves a combination of physical examinations and diagnostic tests to assess liver function and identify the underlying cause.


A thorough physical examination by a veterinarian is the first step in diagnosing liver disease. The vet will look for signs such as jaundice, abdominal pain, and changes in behaviour or appetite. Various diagnostic tests are used to confirm the presence of liver disease and determine its severity.


Blood tests measure levels of liver enzymes, bilirubin, and other indicators of liver function. Abnormal results can suggest liver damage or dysfunction.


Imaging techniques such as ultrasound and X-rays provide a visual assessment of the liver's size, shape, and structure, helping to identify abnormalities like tumours or cysts.


A liver biopsy involves taking a small sample of liver tissue for microscopic examination. It can provide a definitive diagnosis by revealing the specific type of liver disease and the extent of liver damage.


Treatment Options

Treatment for liver disease in cats depends on the underlying cause and the severity of the condition.


Medications may be prescribed to treat infections, reduce inflammation, and manage symptoms such as nausea and pain. In cases of toxic exposure, treatment may involve removing the toxin from the cat's environment and providing supportive care.


Dietary changes are a crucial aspect of managing liver disease. A specialised diet can help support liver function and promote healing.


Specialised diets for cats with liver disease are typically low in protein to reduce the workload on the liver. They also contain specific nutrients that support liver health and aid in the regeneration of liver cells.


In some cases, surgery may be necessary to treat liver disease. This is particularly true if there are blockages, tumours, or other structural issues that need to be addressed.


Prognosis and Recovery

The prognosis for liver disease in cats varies depending on the cause and how early it is detected. With prompt and appropriate treatment, many cats can recover and live healthy lives.


Factors Influencing Recovery

Several factors influence the recovery of cats with liver disease, including the cat's overall health, age, and the underlying cause of the disease. Early diagnosis and treatment are critical for improving the chances of a positive outcome.


Long-term care for cats recovering from liver disease involves regular veterinary check-ups, adherence to dietary recommendations, and monitoring for any signs of recurrence or complications.


Prevention of Liver Disease in Cats

Preventative measures can help reduce the risk of liver disease in cats and ensure their overall health and well-being. Regular veterinary check-ups are essential for early detection of liver disease and other health issues. Routine blood tests and physical examinations can help identify potential problems before they become severe.


Maintaining a healthy diet and weight is important in reducing the risk of liver disease. Obesity is a significant risk factor for hepatic lipidosis, so it is important to provide a balanced diet and encourage regular exercise.


Keeping cats away from harmful substances, including certain foods, plants, and chemicals, is vital for preventing toxic liver damage. It is important to be aware of potential toxins in the home and environment and take steps to keep them out of reach.


Key Takeaways

Awareness and proactive care are key to managing liver disease in cats. By understanding the signs, causes, and treatment options, cat owners can help ensure their feline friends live healthy, happy lives. 


Regular veterinary care, a healthy diet, and a safe environment are crucial for preventing liver disease and promoting overall health.


If your cat's quality of life is suffering, contact our team via 0333 041 8200, or request an appointment.

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